Profiling of 1491 tumors from four HeCOG early breast cancer (eBC) studies using targeted DNA sequencing and central pathology review

Papadopoulou, K., Kourea, H. P., Goussia, A., Korfiatis, N., Koletsa, T., Tzaida, O., Bobos, M., Batistatou, A., Koumarianou, A., Fatorou, E. A., Pectasides, D. G., Christopoulou, A. N., Linardou, H., Fountzilas, E., Pentheroudakis, G., Koutras, A., Psyrri, A., Gogas, H., & Fountzilas, G. (2026). Profiling of 1491 tumors from four HeCOG early breast cancer (eBC) studies using targeted DNA sequencing and central pathology review. ESMO Open, 11, 107057. https://doi.org/10.1016/j.esmoop.2026.107057

Περίληψη

Harmonized clinicogenomic cohorts linking tumor genomics to centrally reviewed pathology are essential for biomarker discovery in early breast cancer. We characterized pathogenic variants (PVs) and examined their associations with centrally assessed subtypes across four HeCOG adjuvant trials.

DOI
10.1016/j.esmoop.2026.107057
Τύπος
Άρθρο σε Περιοδικό
Έτος
2026

Σύνδεσμοι

BibTeX

@article{papadopoulou2026profiling,
title = {Profiling of 1491 tumors from four HeCOG early breast cancer (eBC) studies using targeted DNA sequencing and central pathology review},
author = {K. Papadopoulou and H. P. Kourea and A. Goussia and Nikolaos Korfiatis and T. Koletsa and O. Tzaida and M. Bobos and A. Batistatou and A. Koumarianou and E. Aravantinou Fatorou and D. G. Pectasides and A. N. Christopoulou and H. Linardou and E. Fountzilas and G. Pentheroudakis and A. Koutras and A. Psyrri and H. Gogas and G. Fountzilas},
url = {https://doi.org/10.1016/j.esmoop.2026.107057},
doi = {10.1016/j.esmoop.2026.107057},
year  = {2026},
date = {2026-01-01},
journal = {ESMO Open},
volume = {11},
pages = {107057},
publisher = {Elsevier BV},
abstract = {Harmonized clinicogenomic cohorts linking tumor genomics to centrally reviewed pathology are essential for biomarker discovery in early breast cancer. We characterized pathogenic variants (PVs) and examined their associations with centrally assessed subtypes across four HeCOG adjuvant trials.},
note = {Conference abstract 101P},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

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